KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1B
All Species:
16.36
Human Site:
Y1185
Identified Species:
36
UniProt:
Q00975
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00975
NP_000709.1
2339
262496
Y1185
P
R
N
N
A
L
K
Y
L
D
Y
I
F
T
G
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Y1629
P
R
N
N
A
L
K
Y
L
D
Y
I
F
T
G
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
Y1185
E
R
N
K
V
L
R
Y
F
D
Y
V
F
T
G
Dog
Lupus familis
XP_537779
2046
229120
R923
L
H
P
G
A
Y
F
R
D
L
W
N
I
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O55017
2327
261463
Y1174
F
R
N
N
A
L
K
Y
M
D
Y
I
F
T
G
Rat
Rattus norvegicus
Q02294
2336
262238
Y1183
F
R
N
N
A
L
K
Y
M
D
Y
I
F
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
L982
Y
F
N
L
L
D
L
L
V
V
G
V
S
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
N706
N
S
V
G
A
L
G
N
L
T
L
V
L
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
E727
K
S
K
G
K
K
K
E
E
E
K
K
E
E
E
Honey Bee
Apis mellifera
NP_001159376
1904
215872
G781
F
I
V
L
V
L
F
G
N
Y
T
L
L
N
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
E843
F
T
G
I
F
T
I
E
M
V
L
K
I
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
54.2
80.1
N.A.
91.9
92.1
N.A.
N.A.
38.3
N.A.
20.7
N.A.
44.7
47.6
N.A.
39.5
Protein Similarity:
100
82.3
65.5
82.2
N.A.
94.4
94.5
N.A.
N.A.
53.3
N.A.
36
N.A.
56
58.7
N.A.
52.4
P-Site Identity:
100
100
60
6.6
N.A.
86.6
86.6
N.A.
N.A.
6.6
N.A.
20
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
73.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
20
N.A.
26.6
N.A.
13.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
55
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
10
46
0
0
0
0
19
% D
% Glu:
10
0
0
0
0
0
0
19
10
10
0
0
10
10
10
% E
% Phe:
37
10
0
0
10
0
19
0
10
0
0
0
46
0
0
% F
% Gly:
0
0
10
28
0
0
10
10
0
0
10
0
0
0
46
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
10
0
0
0
0
37
19
0
10
% I
% Lys:
10
0
10
10
10
10
46
0
0
0
10
19
0
0
0
% K
% Leu:
10
0
0
19
10
64
10
10
28
10
19
10
19
19
0
% L
% Met:
0
0
0
0
0
0
0
0
28
0
0
0
0
10
0
% M
% Asn:
10
0
55
37
0
0
0
10
10
0
0
10
0
10
0
% N
% Pro:
19
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
46
0
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
19
0
0
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
10
10
0
0
46
0
% T
% Val:
0
0
19
0
19
0
0
0
10
19
0
28
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
46
0
10
46
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _